Acute pulmonary edema following significant injury to the central nervous system is known as neurogenic pulmonary edema (NPE). drostatic pressure in the development of neurogenic pulmonary edema. The aim of this study is to explore the exact mechanism of epilepsy-induced NPE. Material and methods: The case of a 66-year-old male patient with NPE caused by repeated epileptic seizures is reported. A 21-year-old man had a seizure episode following cranioplasty. Its pathophysiology is multifactorial but largely unknown. We report two cases of NPE and review the literature on NPE cases reported since 1990. • Signs of NPE in computed tomography (CT) examinations were retrospectively assessed in patients admitted for acute seizures. The diagnosis of neurogenic pulmonary edema is based on the occurrence of edema after a neurologic event/insult and the exclusion of other plausible causes. Neurogenic pulmonary edema (NPE) is a relatively rare form of pulmonary edema caused by an increase in pulmonary interstitial and alveolar fluid. Although several episodes of NPE resolve spontaneously, the condition may … The ris ien intracranial pressure, i whics oftehn observed in conjunction with neurogenic pulmonary edema (Ducke anr d Simmons, 1968; Simmons et al., 1968), may be a requirement for th developmene t of pulmonary edema. Neurogenic pulmonary edema (NPE) is characterized by the development of pulmonary edema within minutes to hours of a significant central nervous system (CNS) insult, often resolving spontaneously within 24–48 h [1,2,3].Febrile seizures (FS) is the most common convulsive event, affecting 2–5% of children younger than 60 months [4,5,6,7].The majority of FS cases follow a … We report a case of acute pulmonary oedema after a tonic clonic seizure. ... seizures, and 1% occurred after cerebral trauma. Reported etiologies of neurogenic pulmonary edema are listed in the table . Neurogenic pulmonary oedema as a rare complication of epileptic seizures Abstract Introduction: Neurogenic pulmonary oedema (NPE) is a very rare complication of epileptic seizures, which could potentially increase mortality. In patients with epilepsy mortality due to accidents, asphyxia, cardiac arrhythmias or postictal neurogenic pulmonary oedema (NPO) is twice as high as in the general population. Neurogenic pulmonary edema may be a complication of the terminal phase of cerebral tumors. While many pathogenic theories have been proposed, the exact mechanism remains unclear. Neurogenic pulmonary edema (NPE) is an underdiagnosed clinical entity. Neurogenic pulmonary edema develops within a few hours after a neurologic insult, and diagnosis requires exclusion of other causes of pulmonary edema (eg, high-altitude pulmonary edema). Neurogenic pulmonary edema (NPE) may be involved in seizure-related complications and SUDEP. The mechanism of neurogenic pulmonary edema in epilepsy ... sive seizure-related outpouring of central sympathetic activity, which leads to an increase in pulmonary vascular resistance [13, 14]. NPE has been documented in patients with cere-bral hemorrhage, subarachnoid hemorrhage, cerebral thrombosis, acute open and closed Neurogenic pulmonary edema is an etiological subtype of non-cardiogenic pulmonary edema, classified as a subtype of the acute respiratory distress syndrome by the Berlin definition.. Commonly seen after significant neurological trauma, NPE has also been described after seizure. Epileptic seizures — Among all patients with epilepsy the occurrence of NPE is rare. Neurogenic pulmonary edema is also an increasingly recognized complication of pediatric encephalitis with Enterovirus-71 (Hand, foot, and mouth disease) . 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